Potential karyotypes include one or more additional X chromosomes, Y-chromosomes, or both. Alcohol Clin Supernumerary x-chromosome sex linked traits in Sydney Res. Introduction to Genomics. Genome Biol. IQ was significantly lower in the 49,XXY group Microduplication of 15q Moreover, differences in brain morphology have been associated with imprinting of the X-chromosome in Turner Syndrome, indicating that the parental origin of the X-chromosome may be important in mediating the psychiatric symptoms present in sex abnormalities.
Psychol Med. Decreased volumes were also seen in a variety of gray matter regions, including areas containing the amygdala, hippocampus, cingulate, insula, and temporal and occipital gyri. Structural imaging measurement of brain volumes including total gray and white matter, lobar measures, caudate volume, cross-sectional area of the corpus callosum, and cortical thickness were obtained using an automated pipeline [ Zijdenbos et al.
Liss; X-linked genes and mental functioning. The most strongly affected regions were supernumerary x-chromosome sex linked traits in Sydney the motor strip, temporal, inferior parietal, and inferior left frontal regions, whereas cortical thickness was preserved in the superior parietal regions.
In the Denver study, an unselected cohort of 40, consecutive newborns were screened for SCAs in Denver between and and followed from birth to adulthood [ Bender et al. However, a growing body of literature [ Arnold, ] is now suggesting that differences in the neural expression of X and Y genes may be more prominent than supernumerary x-chromosome sex linked traits in Sydney appreciated [ Vawter et al.
In: Poustka F, editor.
R package version 1. Eur Child Adolesc Psychiatry. Brain imaging results showed no significant differences in brain volumes between 47,XYY and controls, although white matter hyperintensities were found in one of the 47,XYY subjects and no controls. This would be further supported by a case study of a 6 year female who showed extensive white matter hyperintensities on T2 weighted and FLAIR images [ Garcia-Cazorla et al.