Corresponding author. Mod Pathol. The relationship of treatment to overall survival will be assessed using the proportional hazards model. In this age group, other differential diagnosis such as polycystic ovary syndrome and adrenal androgen-secreting tumors should be considered.
N Engl J Med.
E and F Gynandroblastomas feature a combination of juvenile granulosa cell tumor E and Sertoli-Leydig cell tumor F features. Ovarian tumors associated with multiple endocrine neoplasias and related syndromes Carney complex, Peutz-Jeghers syndrome, von Hippel-Lindau disease, Cowden's disease. Material reproduced from Martins I, et al.
The pseudolobular areas in the outer part of the lesion commonly exhibit a spoke-wheel pattern and iso- to hypointensity on T2-weighted imaging in contrast with the hyperintense septa 1518 Fig.
Ovarian fibromas and fibrothecomas: sonographic correlation mixed sex cord stromal tumor of ovary in Peoria computed tomography and magnetic resonance imaging: a 5-year single-institution experience. Author information Article notes Copyright and License information Disclaimer.
In such cases, hemorrhagic infarction or necrosis may occur 3 Benign and malignant ovarian steroid cell tumors, not otherwise specified: case studies, comparison, and review of the literature. However, in contrast to endometrial stromal nodules, intravascular typically intravenous worm-like plugs of tumor are variably present within the myometrium and para-uterine soft tissues the latter easier to identify.
Generally, pure thecomas or thecomas with scanty fibrotic components do not have distinct US and CT appearances and mimic other solid ovarian tumors The described US features may mimic those of malignant ovarian tumors; therefore, further MRI-based radiologic evaluation is usually necessary.
However LOH was found in only one case, suggesting that this gene does not function as a tumour suppressor gene in granulosa cell tumours in human, contrary to the findings in the mouse model.